Article
Association between ins4436A in 11β-hydroxysteroid dehydrogenase type 1 gene and essential hypertension in Polish population.
Postepy higieny i medycyny doswiadczalnej (Online) - 17 Nov 2015
Hejduk Paulina, Sakowicz Agata, Pietrucha Tadeusz
Abstract excerpt
BACKGROUND: Essential hypertension (EH) is the most common cardiovascular disease worldwide, and it has a strong genetic component. Cortisol homeostasis is an important factor in controlling blood pressure, and the availability of this hormone is regulated by 11βhydroxysteroid dehydrogenase type 1 enzyme (11βHSD1), which converts cortisone into cortisol. MATERIALS AND METHODS: We investigated the correlation...
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