Article
Association of AGTR1 (rs5186), VDR (rs2228570) genes polymorphism with blood pressure elevation in patients with essential arterial hypertension.
Journal of medicine and life - 1 Jan 2000
Semianiv Marianna Mykolaivna, Sydorchuk Larysa Petrivna, Dzhuryak Valentyna Stepanivna, Gerush Oleg Vasylovich, Vasylovich Gerush Oleg, Palamar Alina Oleksandrivna, Muzyka Natalia Yaroslavivna, Korovenkova Oksana Mykolaivna, Blazhiievska Olesia Mykhaylivna, Sydor Valeriia Valeriivna, Sydorchuk Andrii Ruslanovich, Semianiv Igor Oleksandrovich, Sydorchuk Ruslan Igorovich
Abstract excerpt
Essential arterial hypertension (EAH) is a polygenic disease due to environmental, genetic, and epigenomic factors. The study aimed to establish the association of single nucleotide polymorphism (SNP) of AGTR1 (rs5186) and VDR (rs2228570) genes with the blood pressure (BP) elevation in EAH patients. 100 EAH subjects with hypertensive-mediated organ damaging (2nd stage), moderate, high, or very high cardiovascular...
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