Article
CYP11B2 gene polymorphism and essential hypertension among Tibetan, Dongxiang and Han populations from northwest of China.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2000
Li Xinghui, Xie Ping, He Jin, Cai Hui, Yang Ruixuan, Zhang Qing, Li Baojuan, Qi Wenhua, Ma Haizhong
Abstract excerpt
Essential hypertension (EH) is a complex multifactorial condition influenced by both genetic and environmental factors; aldosterone synthase (CYP11B2) is a key enzyme which involves in the terminal steps of aldosterone synthesis. The result of relationship between C-344T of CYP11B2 polymorphism and EH was controversial. This study was undertaken to investigate the association of C-344T polymorphism with EH in the...
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