Article
CYP4A11 gene T8590C polymorphism is associated with essential hypertension in the male western Chinese Han population.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2014
Yang Hong, Fu Zhenyan, Ma Yitong, Huang Ding, Zhu Qing, Erdenbat Cha, Xie Xiang, Liu Fen, Zheng Yingying
Abstract excerpt
BACKGROUND: CYP4A11 is a member of the cytochrome P450 enzymes and is responsible for metabolizing arachidonic acid to 20-hydroxyeicosatetraenoic acid, a metabolite involved in the regulation of blood pressure. This study aimed to evaluate whether or not the CYP4A11 gene polymorphism T8590C (rs1126742) is involved in essential hypertension in the western Chinese Han population. METHODS: In a case-control study,...
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