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Article

Association between polymorphisms in the renin-angiotensin-aldosterone system genes and essential hypertension in the Han Chinese population.

PloS one - 1 Jan 2013

Ji Lindan, Cai Xiaobo, Zhang Lina, Fei Lijuan, Wang Lin, Su Jia, Lazar Lissy, Xu Jin, Zhang Yaping

Abstract excerpt

BACKGROUND: Renin-angiotensin-aldosterone system (RAAS) is the most important endocrine blood pressure control mechanism in our body, genes encoding components of this system have been strong candidates for the investigation of the genetic basis of hypertension. However, previous studies mainly focused on limited polymorphisms, thus we carried out a case-control study in the Han Chinese population to systemically...

Topics

Adult
Aged
Asian People
Body Mass Index
China
Cytochrome P-450 CYP11B2
Female
Genetic Predisposition to Disease
Humans
Hypertension
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Peptidyl-Dipeptidase A

Polymorphism, Single Nucleotide

Receptor, Angiotensin, Type 1

Renin-Angiotensin System

Source

Open in PubMed Open full text

Identifiers

PMID: 24015270
DOI: 10.1371/journal.pone.0072701
PMCID: PMC3756014

Genes

ACE
AGT
AGTR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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