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Systematic pan-cancer analysis of tumour purity

4 Dec 2015

Abstract excerpt

The tumour microenvironment is the non-cancerous cells present in and around a tumour, including mainly immune cells, but also fibroblasts and cells that comprise supporting blood vessels. These non-cancerous components of the tumour may play an important role in cancer biology. They also have a strong influence on the genomic analysis of tumour samples, and may alter the biological interpretation of results....

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PMID: 26634437
DOI: 10.1038/ncomms9971

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