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Article

Systematic Assessment of Tumor Purity and Its Clinical Implications

4 Sept 2020

Abstract excerpt

PURPOSE: The tumor microenvironment is complex, comprising heterogeneous cellular populations. As molecular profiles are frequently generated using bulk tissue sections, they represent an admixture of multiple cell types (including immune, stromal, and cancer cells) interacting with each other. Therefore, these molecular profiles are confounded by signals emanating from many cell types. Accurate assessment of...

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PMID: 33015524
DOI: 10.1200/po.20.00016

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