Article
Tumor Purity as an Underlying Key Factor in Glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2017
Zhang Chuanbao, Cheng Wen, Ren Xiufang, Wang Zheng, Liu Xing, Li Guanzhang, Han Sheng, Jiang Tao, Wu Anhua
Abstract excerpt
Purpose: Glioma tissues consist of not only glioma cells but also glioma-associated nontumor cells, such as stromal cells and immune cells. These nontumor cells dilute the purity of glioma cells and play important roles in glioma biology. Currently, the implications of variation in glioma purity are not sufficiently clarified.Experimental Design: Here, tumor purity was inferred for 2,249 gliomas and 29 normal...
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