Article

Comprehensive Benchmarking and Integration of Tumour Microenvironment Cell Estimation Methods

2018-10-08

Abstract excerpt

<h4>ABSTRACT</h4> The tumour microenvironment comprises complex cellular compositions and interactions between cancer, immune, and stromal components which all play crucial roles in cancer. Various computational approaches have been developed during the last decade that estimate the relative abundance of different cell types in an unbiased manner using bulk tumour RNA data. However, a comparison that objectively...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 998929c5-cc84-566d-be5d-8692c9b917dd
DOI: 10.1101/437533

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comprehensive Benchmarking and Integration of Tumour Microenvironment Cell Estimation MethodsDOI 10.1101/437533Read

Pan-cancer classification of single cells in the tumour microenvironmentSemantic proximity Read

Pan-cancer classification of single cells in the tumour microenvironmentSemantic proximity Read

Estimation of immune cell content in tumour tissue using single-cell RNA-seq dataSemantic proximity Read

Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression dataSemantic proximity Read

Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression dataSemantic proximity Read

Single-Cell Analysis of the Pan-Cancer Immune Microenvironment and scTIME PortalSemantic proximity Read

CHARTS: A web application for characterizing and comparing tumor subpopulations in publicly available single-cell RNA-seq datasetsSemantic proximity Read

AI-based separation of malignant cell- and microenvironment-specific gene expression from bulk RNA sequencing enhances biomarker interpretationSemantic proximity Read

TIMEDB: tumor immune micro-environment cell composition database with automatic analysis and interactive visualizationSemantic proximity Read

Systematic pan-cancer analysis of tumour puritySemantic proximity Read

Predicting tumor immune microenvironment and checkpoint therapy response of head & neck cancer patients from blood immune single-cell transcriptomicsSemantic proximity Read

Inferring tumour purity and stromal and immune cell admixture from expression dataSemantic proximity Read