Article

Estimation of immune cell content in tumour tissue using single-cell RNA-seq data

2017-04-12

Abstract excerpt

As interactions between the immune system and tumour cells are governed by a complex network of cell-cell interactions, knowing the specific immune cell composition of a solid tumour may be essential to predict a patient’s response to immunotherapy. Here, we analyse in depth how to derive the cellular composition of a solid tumour from bulk gene expression data by mathematical deconvolution, using indication- and...

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Literature Corpus work: 6578bc9c-512b-590c-a6af-3466602b5a5b
DOI: 10.1101/127001

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