Article

Tumour purity as a prognostic factor in colon cancer

2018-02-12

Abstract excerpt

Tumour purity is defined as the proportion of cancer cells in the tumour tissue. The impact of tumour purity on colon cancer (CC) prognosis, genetic profile and microenvironment has not been thoroughly accessed. Therefore, clinical and transcriptomic data from three public datasets, GSE17536/17537, GSE39582, and TCGA were retrospectively collected (n = 1248). Tumour purity of each sample was inferred by a computat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 13fcc051-0ef8-53c3-85eb-4844a42147cf
DOI: 10.1101/263723

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Tumour purity as a prognostic factor in colon cancerDOI 10.1101/263723Read

Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancerSemantic proximity Read

Tumor purity as a prognosis and immunotherapy relevant feature in gastric cancer.Semantic proximity Read

Metastatic colorectal adenocarcinoma tumor purity assessment from whole exome sequencing data.Semantic proximity Read

Tumour purity as an underlying key factor in tumour mutation detection in colorectal cancerSemantic proximity Read

Systematic pan-cancer analysis of tumour puritySemantic proximity Read

Tumor Purity as an Underlying Key Factor in Glioma.Semantic proximity Read

Development and validation of a gene expression score to account for tumour purity and improve prognostication in breast cancerSemantic proximity Read

Tumor purity–associated genes influence hepatocellular carcinoma prognosis and tumor microenvironmentSemantic proximity Read

The Good, the Bad and the Ugly - Novel Synoptic Variables in the Personalisation of Colon Cancer TreatmentSemantic proximity Read

Impact of Tumor Purity on Immune Gene Expression and Clustering Analyses across Multiple Cancer Types.Semantic proximity Read

Malignant Tumor Purity Reveals the Driven and Prognostic Role of CD3E in Low-Grade Glioma MicroenvironmentSemantic proximity Read

Weakly-Supervised Tumor Purity Prediction From Frozen H&E Stained SlidesSemantic proximity Read