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Article

Targeted re-sequencing of linkage region on 2q21 identifies a novel functional variant for hip and knee osteoarthritis.

Osteoarthritis and cartilage - 1 Apr 2016

Taipale M, Jakkula E, Kämäräinen O-P, Gao P, Skarp S, Barral S, Kiviranta I, Kröger H, Ott J, Wei G-H, Ala-Kokko L, Männikkö M

Abstract excerpt

OBJECTIVE: The aim of the study was to identify genetic variants predisposing to primary hip and knee osteoarthritis (OA) in a sample of Finnish families. METHODS: Genome wide analysis was performed using 15 independent families (279 individuals) originating from Central Finland identified as having multiple individuals with primary hip and/or knee OA. Targeted re-sequencing was performed for three samples from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26603474
DOI: 10.1016/j.joca.2015.10.019

Genes

ELF3
HMGA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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