Article

Identification of Novel Genetic Variants Associated with Knee Osteoarthritis Patients of South India using Whole Exome Sequencing

2025-11-10

Abstract excerpt

<title>Abstract</title> <p> Knee Osteoarthritis is the most prevalent form of arthritis. It is a major contributor to disability worldwide. Its aetiology is multifactorial, involving genetic predisposition and environmental influences. Despite extensive investigation in European and East Asian populations, the genetic basis of kOA in South Indians remains largely unexplored. In this study, whole-exome sequencing...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0afa9d2d-f4a0-5bbc-b636-c15734aa2991
DOI: 10.21203/rs.3.rs-7434154/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of Novel Genetic Variants Associated with Knee Osteoarthritis Patients of South India using Whole Exome SequencingDOI 10.21203/rs.3.rs-7434154/v1Read

Identification of novel genetic variations affecting osteoarthritis patients.Semantic proximity Read

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.Semantic proximity Read

The genetic architecture of osteoarthritis: insights from UK BiobankSemantic proximity Read

The Genetic Epidemiological Landscape of Hip and Knee Osteoarthritis: Where Are We Now and Where Are We Going?Semantic proximity Read

Rare variant association studies: Significance, methods, and applications in chronic pain studies.Semantic proximity Read

Osteoarthritis year in review: genetics, genomics, epigenetics.Semantic proximity Read

Advances in osteoarthritis genetics.Semantic proximity Read

Structural phenotypes of osteoarthritis are clinically and genetically distinct: findings from 59,539 UK Biobank participantsSemantic proximity Read

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.Semantic proximity Read

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.Semantic proximity Read

Putative functional variants of lncRNA identified by RegulomeDB were associated with knee osteoarthritis susceptibility.Semantic proximity Read

SAGE: a comprehensive resource of genetic variants integrating South Asian whole genomes and exomes.Semantic proximity Read