Article
Roles of Puf proteins in mRNA degradation and translation.
Wiley interdisciplinary reviews. RNA - 1 Jan 2000
Miller Melanie A, Olivas Wendy M
Abstract excerpt
Puf proteins are regulators of diverse eukaryotic processes including stem cell maintenance, organelle biogenesis, oogenesis, neuron function, and memory formation. At the molecular level, Puf proteins promote translational repression and/or degradation of target mRNAs by first interacting with conserved cis-elements in the 3' untranslated region (UTR). Once bound to an mRNA, Puf proteins elicit RNA repression by...
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