Article
The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast.
The EMBO journal - 1 Dec 2000
Olivas W, Parker R
Abstract excerpt
Eukaryotic post-transcriptional regulation is often specified by control elements within mRNA 3'- untranslated regions (3'-UTRs). In order to identify proteins that regulate specific mRNA decay rates in Saccharomyces cerevisae, we analyzed the role of five members of the Puf family present in the yeast genome (referred to as JSN1/PUF1, PUF2, PUF3, PUF4 and MPT5/PUF5). Yeast strains lacking all five Puf proteins...
Topics
- 3' Untranslated Regions
- Alleles
- Animals
- Base Sequence
- Blotting, Northern
- Blotting, Western
- Caenorhabditis elegans
- Cation Transport Proteins
- Copper Transport Proteins
- Drosophila
- Models, Genetic
- Molecular Chaperones
- Molecular Sequence Data
- Multigene Family
