Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel insights into global translational regulation through Pumilio family RNA-binding protein Puf3p revealed by ribosomal profiling.

Current genetics - 1 Feb 2019

Wang Zhe, Sun Xuepeng, Wee Josephine, Guo Xiaoxian, Gu Zhenglong

Abstract excerpt

RNA binding proteins (RBPs) can regulate the stability, localization, and translation of their target mRNAs. Among them, Puf3p is a well-known Pumilio family RBP whose biology has been intensively studied. Nevertheless, the impact of Puf3p on the translational regulation of its downstream genes still remains to be investigated at the genome-wide level. In this study, we combined ribosome profiling and RNA-Seq in...

Topics

Carbohydrate Metabolism
Gene Expression Regulation, Fungal
Gene Ontology
Gene Regulatory Networks
Genome, Fungal
Mitochondria
Mutation
Protein Biosynthesis
RNA-Binding Proteins
Ribosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Sequence Analysis, RNA

Source

Open in PubMed Open full text

Identifiers

PMID: 29951697
DOI: 10.1007/s00294-018-0862-4
PMCID: PMC6666313

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel insights into global translational regulation through Pumilio family RNA-binding protein Puf3p revealed by ribosomal profiling.PMID 29951697Read ↗

The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast.Semantic proximity Read ↗

Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast.Semantic proximity Read ↗

Global analysis of ribosome-associated noncoding RNAs unveils new modes of translational regulation.Semantic proximity Read ↗

Evolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA Targets.Semantic proximity Read ↗

A role for the poly(A)-binding protein Pab1p in PUF protein-mediated repression.Semantic proximity Read ↗

Decoding regulatory specificity of human ribosomal proteinsSemantic proximity Read ↗

The global translation profile in a ribosomal protein mutant resembles that of an eIF3 mutant.Semantic proximity Read ↗

Plant PUF RNA-binding proteins: A wealth of diversity for post-transcriptional gene regulation.Semantic proximity Read ↗

AtPRMT3-RPS2B promotes ribosome biogenesis and coordinates growth and cold adaptation trade-off.Semantic proximity Read ↗

Puf6 and Loc1 Are the Dedicated Chaperones of Ribosomal Protein Rpl43 in Saccharomyces cerevisiae.Semantic proximity Read ↗

Principles of mRNA control by human PUM proteins elucidated from multi-modal experiments and integrative data analysisSemantic proximity Read ↗

Tom20 mediates localization of mRNAs to mitochondria in a translation-dependent manner.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.