Article
Characterization of circulating APOL1 protein complexes in African Americans.
Journal of lipid research - 1 Jan 2016
Weckerle Allison, Snipes James A, Cheng Dongmei, Gebre Abraham K, Reisz Julie A, Murea Mariana, Shelness Gregory S, Hawkins Gregory A, Furdui Cristina M, Freedman Barry I, Parks John S, Ma Lijun
Abstract excerpt
APOL1 gene renal-risk variants are associated with nephropathy and CVD in African Americans; however, little is known about the circulating APOL1 variant proteins which reportedly bind to HDL. We examined whether APOL1 G1 and G2 renal-risk variant serum concentrations or lipoprotein distributions differed from nonrisk G0 APOL1 in African Americans without nephropathy. Serum APOL1 protein concentrations were...
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