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Article

The biology of APOL1 with insights into the association between APOL1 variants and chronic kidney disease.

Clinical and experimental nephrology - 1 Apr 2014

Madhavan Sethu M, O'Toole John F

Abstract excerpt

Recent studies have identified genetic variants in APOL1 that may contribute to the increased incidence of kidney disease in populations with African ancestry. Here, we review the biology of APOL1 present in the circulation and localized to the kidney as it may contribute to the pathogenesis of APOL1-associated kidney disease.

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Topics

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Share to Apolipoprotein L1
Share to Apolipoproteins
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Lipoproteins, HDL

Share to Polymorphism, Single Nucleotide

Share to Renal Insufficiency, Chronic

Share to Trypanosomiasis, African

Source

Open in PubMed Open full text

Identifiers

PMID: 24233469
DOI: 10.1007/s10157-013-0907-4
PMCID: PMC4022720

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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