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Article

Involvement of loop 5 lysine residues and the N-terminal β-hairpin of the ribotoxin hirsutellin A on its insecticidal activity.

Biological chemistry - 1 Jan 2016

Olombrada Miriam, García-Ortega Lucía, Lacadena Javier, Oñaderra Mercedes, Gavilanes José G, Martínez-del-Pozo Álvaro

Abstract excerpt

Ribotoxins are cytotoxic members of the family of fungal extracellular ribonucleases best represented by RNase T1. They share a high degree of sequence identity and a common structural fold, including the geometric arrangement of their active sites. However, ribotoxins are larger, with a well-defined N-terminal β-hairpin, and display longer and positively charged unstructured loops. These structural differences...

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PMID: 26584355
DOI: 10.1515/hsz-2015-0261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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