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Article

Role of the basic character of alpha-sarcin's NH2-terminal beta-hairpin in ribosome recognition and phospholipid interaction.

Archives of biochemistry and biophysics - 1 Jan 2009

Alvarez-García Elisa, Martínez-del-Pozo Alvaro, Gavilanes José G

Abstract excerpt

Ribotoxins are a family of toxic extracellular fungal RNases that first enter into the cells and then exert a highly specific ribonucleolytic activity on the larger rRNA molecule, leading to protein synthesis inhibition and cell death by apoptosis. alpha-Sarcin is the best characterized ribotoxin. Previous characterization of a deletion variant of this protein showed that its long NH(2)-terminal beta-hairpin is...

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PMID: 18952045
DOI: 10.1016/j.abb.2008.10.012

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SRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of the basic character of alpha-sarcin's NH2-terminal beta-hairpin in ribosome recognition and phospholipid interaction.PMID 18952045Read ↗

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