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Article

Genome-wide mapping of Hif-1α binding sites in zebrafish.

BMC genomics - 11 Nov 2015

Greenald David, Jeyakani Justin, Pelster Bernd, Sealy Ian, Mathavan Sinnakaruppan, van Eeden Fredericus J

Abstract excerpt

BACKGROUND: Hypoxia Inducible Factor (HIF) regulates a cascade of transcriptional events in response to decreased oxygenation, acting from the cellular to the physiological level. This response is evolutionarily conserved, allowing the use of zebrafish (Danio rerio) as a model for studying the hypoxic response. Activation of the hypoxic response can be achieved in zebrafish by homozygous null mutation of the von...

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Identifiers

PMID: 26559940
DOI: 10.1186/s12864-015-2169-x
PMCID: PMC4642629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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