Article
Genetic analysis of hypoxia signaling and response in C elegans.
Annals of the New York Academy of Sciences - 1 May 2003
Shen Chuan, Powell-Coffman Jo Anne
Abstract excerpt
During normal development and homeostasis, animals use cellular and systemic strategies to adapt to changing oxygen levels. In mammals, hypoxic tissues secrete growth factors to induce angiogenesis, and individual cells increase anaerobic metabolism in order to sustain basic cellular functions. M...
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