Article
Translational misreading in Mycobacterium smegmatis increases in stationary phase.
Tuberculosis (Edinburgh, Scotland) - 1 Dec 2015
Leng Tianqi, Pan Miaomiao, Xu Xin, Javid Babak
Abstract excerpt
The study of errors in gene translation has largely been confined to a small number of model organisms. We have examined all possible misreading errors at a defined codon in Mycobacterium smegmatis. Using a dual-luciferase gain of function reporter system that employs a mutated essential lysine in firefly luciferase, we accurately quantified mistranslation errors. Overall, accuracy of gene translation was...
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