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Article

Genomic dynamics associated with malignant transformation in IDH1 mutated gliomas.

Oncotarget - 22 Dec 2015

Park Chul-Kee, Park Inho, Lee Seungmook, Sun Choong-Hyun, Koh Youngil, Park Sung-Hye, Kim Ja Eun, Yun Hongseok, Lee Se-Hoon

Abstract excerpt

The genomic mechanism responsible for malignant transformation remains an open question for glioma researchers, where differing conclusions have been drawn based on diverse study conditions. Therefore, it is essential to secure direct evidence using longitudinal samples from the same patient. Moreover, malignant transformation of IDH1-mutated gliomas is of potential interest, as its genomic mechanism under...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26524630
DOI: 10.18632/oncotarget.6189
PMCID: PMC4791257

Genes

IDH1
TCF12

Provenance

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