Article

Unraveling the tumor-promoting role of wildtype Isocitrate dehydrogenase 1 (IDH1) in human gliomas

2024-03-28

Abstract excerpt

<title>Abstract</title> <p><italic>Isocitrate dehydrogenase 1</italic> (<italic>IDH1</italic>) mutations are discovered in most grade Ⅱ gliomas (71%-78%), grade Ⅲ gliomas (62%-78%) and secondary glioblastomas (88%), and have received lots of attention in recent years. However, the tumor-promoting role of wildtype IDH1 still need to be further investigated. In this article, we found wildtype IDH1 mRNA and protein...

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Literature Corpus work: 9eb39c2a-c1e9-561b-8d48-7d8b99cede24
DOI: 10.21203/rs.3.rs-4043926/v1

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