Article
A Unique Plasmodium falciparum K13 Gene Mutation in Northwest Ethiopia.
The American journal of tropical medicine and hygiene - 1 Jan 2016
Bayih Abebe Genetu, Getnet Gebeyaw, Alemu Abebe, Getie Sisay, Mohon Abu Naser, Pillai Dylan R
Abstract excerpt
Artemisinin combination therapy (ACT) is the first line to treat uncomplicated Plasmodium falciparum malaria worldwide. Artemisinin treatment failures are on the rise in southeast Asia. Delayed parasite clearance after ACT is associated with mutations of the P. falciparum kelch 13 gene. Patients (N = 148) in five districts of northwest Ethiopia were enrolled in a 28-day ACT trial. We identified a unique kelch 13...
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