Article
Polymorphisms in the K13 Gene in Plasmodium falciparum from Different Malaria Transmission Areas of Kenya.
The American journal of tropical medicine and hygiene - 1 May 2018
de Laurent Zaydah R, Chebon Lorna J, Ingasia Luicer A, Akala Hoseah M, Andagalu Ben, Ochola-Oyier Lynette Isabella, Kamau Edwin
Abstract excerpt
The development of artemisinin (ART)-resistant parasites in Southeast Asia (SEA) threatens malaria control globally. Mutations in the Kelch 13 (K13)-propeller domain have been useful in identifying ART resistance in SEA. ART combination therapy (ACT) remains highly efficacious in the treatment of uncomplicated malaria in Sub-Saharan Africa (SSA). However, it is crucial that the efficacy of ACT is closely...
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