Article
Surveillance of molecular markers of Plasmodium falciparum artemisinin resistance (kelch13 mutations) in Papua New Guinea between 2016 and 2018.
International journal for parasitology. Drugs and drug resistance - 1 Aug 2021
Lautu-Gumal Dulcie, Razook Zahra, Koleala Tamarah, Nate Elma, McEwen Samuel, Timbi Diana, Hetzel Manuel W, Lavu Evelyn, Tefuarani Nakapi, Makita Leo, Kazura James, Mueller Ivo, Pomat William, Laman Moses, Robinson Leanne J, Barry Alyssa E
Abstract excerpt
Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) is a global threat to malaria control and elimination efforts. Mutations in the P. falciparum kelch13 gene (Pfk13) that are associated with delayed parasite clearance have emerged on the Thai-Cambodian border since 2008. There is growing evidence of widespread Pfk13 mutations throughout South-East Asia and they have independently...
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