Article

Expansion of the Plasmodium falciparum Kelch 13 R622I mutation in Northwest Ethiopia

2021-03-17

Abstract excerpt

<title>Abstract</title> <p>According to the WHO, almost two thirds of the Ethiopian population are at risk of contracting malaria, where infection with Plasmodium falciparum accounts for approximately 60% of cases today. The risk of artemisinin resistance spreading from SE Asia to Africa is a major concern. We conducted a 28-day <italic>in vivo</italic> efficacy trial of Artemether-Lumefantrine (Co-Artem) for tre...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 77088969-2f66-5ca2-81dc-03d9fa5101b3
DOI: 10.21203/rs.3.rs-171038/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Expansion of the Plasmodium falciparum Kelch 13 R622I mutation in Northwest EthiopiaDOI 10.21203/rs.3.rs-171038/v1Read

A Unique Plasmodium falciparum K13 Gene Mutation in Northwest Ethiopia.Semantic proximity Read

Incidence of kelch13 and Pfmdr1 gene mutations associated with antimalarial drug resistance in Plasmodium falciparum isolates from Ethiopia: a systematic review and meta-analysis.Semantic proximity Read

Therapeutic Efficacy of Artemether-Lumefantrine (AL) plus Single Low Dose Primaquine for the treatment of uncomplicated <i>falciparum</i> malaria in a high transmission setting, Western EthiopiaSemantic proximity Read

Molecular surveillance of Kelch 13 polymorphisms in Plasmodium falciparum isolates from Kenya and Ethiopia.Semantic proximity Read

Artemisinin resistant <i>kelch13</i> R622I and RDT negativity approaching predominance in northern Ethiopia and emerging C580Y of African origin threaten falciparum malaria controlSemantic proximity Read

Functional validation of the <i>Plasmodium falciparum</i> K13 C580Y mutation in recently collected Ethiopian isolatesSemantic proximity Read

A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa.Semantic proximity Read

Clonal spread of<i>Plasmodium falciparum</i>candidate artemisinin partial resistance<i>Kelch13</i>622I mutation and co-occurrence with<i>pfhrp2/3</i>deletions in EthiopiaSemantic proximity Read

Clinical evidence of Kelch13-dependent and -independent malaria treatment failure with Artemether-LumefantrineSemantic proximity Read

Plasmodium falciparum kelch 13 Mutations, 9 Countries in Africa, 2014-2018.Semantic proximity Read

Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in EthiopiaSemantic proximity Read

Kelch 13-propeller polymorphisms in Plasmodium falciparum from Jazan region, southwest Saudi Arabia.Semantic proximity Read