A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa.

doi:10.1016/j.ijpddr.2021.06.001

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Article

A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa.

International journal for parasitology. Drugs and drug resistance - 1 Aug 2021

Ndwiga Leonard, Kimenyi Kelvin M, Wamae Kevin, Osoti Victor, Akinyi Mercy, Omedo Irene, Ishengoma Deus S, Duah-Quashie Nancy, Andagalu Ben, Ghansah Anita, Amambua-Ngwa Alfred, Tukwasibwe Stephen, Tessema Sofonias K, Karema Corine, Djimde Abdoulaye A, Dondorp Arjen M, Raman Jaishree, Snow Robert W, Bejon Philip, Ochola-Oyier Lynette Isabella

Abstract excerpt

Artemisinin resistance (AR) emerged in South East Asia 13 years ago and the identification of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 years ago has provided an invaluable tool for monitoring AR in malaria endemic countries. Molecular Pfk13 surveillance revealed the resistance foci in the Greater Mekong Subregion, an independent emergence in Guyana, South America, and...

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PMID: 34146993
DOI: 10.1016/j.ijpddr.2021.06.001
PMCID: PMC8219943

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