Article
Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms.
Epigenetics - 1 Jan 2015
Fisher Helen L, Murphy Therese M, Arseneault Louise, Caspi Avshalom, Moffitt Terrie E, Viana Joana, Hannon Eilis, Pidsley Ruth, Burrage Joe, Dempster Emma L, Wong Chloe C Y, Pariante Carmine M, Mill Jonathan
Abstract excerpt
Childhood psychotic symptoms are associated with increased rates of schizophrenia, other psychiatric disorders, and suicide attempts in adulthood; thus, elucidating early risk indicators is crucial to target prevention efforts. There is considerable discordance for psychotic symptoms between monozygotic twins, indicating that child-specific non-genetic factors must be involved. Epigenetic processes may constitute...
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