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Article

Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia

13 Oct 2014

Abstract excerpt

BACKGROUND: Schizophrenia is a severe neuropsychiatric disorder that is hypothesized to result from disturbances ine arly brain development. There is mounting evidence to support a role for developmentally regulated epigenetic variation in the molecular etiology of the disorder. Here, we describe a systematic study of schizophrenia-associated methylomic variation in the adult brain and its relationship to changes...

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Share to Epigenetics and DNA Methylation
Share to Genetic Associations and Epidemiology
Share to Schizophrenia research and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25347937
DOI: 10.1186/s13059-014-0483-2

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