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Article

Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder.

Human molecular genetics - 15 Dec 2011

Dempster Emma L, Pidsley Ruth, Schalkwyk Leonard C, Owens Sheena, Georgiades Anna, Kane Fergus, Kalidindi Sridevi, Picchioni Marco, Kravariti Eugenia, Toulopoulou Timothea, Murray Robin M, Mill Jonathan

Abstract excerpt

Studies of the major psychoses, schizophrenia (SZ) and bipolar disorder (BD), have traditionally focused on genetic and environmental risk factors, although more recent work has highlighted an additional role for epigenetic processes in mediating susceptibility. Since monozygotic (MZ) twins share a common DNA sequence, their study represents an ideal design for investigating the contribution of epigenetic factors...

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Identifiers

PMID: 21908516
DOI: 10.1093/hmg/ddr416
PMCID: PMC3221539

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Source receipt: pubmed, retrieved 7 Sept 2026.

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