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Article

DNA methylation differences in monozygotic twin pairs discordant for schizophrenia identifies psychosis related genes and networks.

BMC medical genomics - 6 May 2015

Castellani Christina A, Laufer Benjamin I, Melka Melkaye G, Diehl Eric J, O'Reilly Richard L, Singh Shiva M

Abstract excerpt

BACKGROUND: Despite their singular origin, monozygotic twin pairs often display discordance for complex disorders including schizophrenia. It is a common (1%) and often familial disease with a discordance rate of ~50% in monozygotic twins. This high discordance is often explained by the role of yet unknown environmental, random, and epigenetic factors. The involvement of DNA methylation in this disease appears...

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Identifiers

PMID: 25943100
DOI: 10.1186/s12920-015-0093-1
PMCID: PMC4494167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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