Article
Interethnic relationships of CYP2D6 variants in native and Mestizo populations sharing the same ecosystem.
Pharmacogenomics - 1 Jan 2015
Perez-Paramo Yadira Xitlalli, Hernandez-Cabrera Francisco, Dorado Pedro, Llerena Adrian, Muñoz-Jimenez Sergio, Ortiz-Lopez Rocio, Rojas-Martinez Augusto
Abstract excerpt
AIM: To analyze the distribution of CYP2D6 variants in two ethnically-related Mexican Native and Mestizo populations cohabitating the same econiche and their relationships with a distant Mestizo community. MATERIALS & METHODS: 314 volunteers were genotyped for CYP2D6 gene variants (*2, *3, *4, *6, *10, *13, *17, *35 and *41) using predesigned TaqMan probes. CYP2D6*5 and CYP2D6 wtxN were assessed by XL-PCR....
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