Article
A metric and workflow for quality control in the analysis of heterogeneity in phenotypic profiles and screens.
Methods (San Diego, Calif.) - 1 Mar 2016
Gough Albert, Shun Tong Ying, Lansing Taylor D, Schurdak Mark
Abstract excerpt
Heterogeneity is well recognized as a common property of cellular systems that impacts biomedical research and the development of therapeutics and diagnostics. Several studies have shown that analysis of heterogeneity: gives insight into mechanisms of action of perturbagens; can be used to predict optimal combination therapies; and can be applied to tumors where heterogeneity is believed to be associated with...
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