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Article

Quality Control Measures and Statistical Strategies to Address the Challenges of High-Content Phenotypic Data.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2026

Pearson Yanthe E, Gunsalus Kristin C

Abstract excerpt

High-content image-based cytological profiling is a powerful strategy for studying the effects of chemical and genetic perturbations on the cell. Cytological profiling assays illuminate multiple cellular compartments within each cell by multiplex fluorescent staining, followed by automated microscopy and image analysis. In this chapter, we show how to utilize data derived from images of fluorescently labeled...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41479051
DOI: 10.1007/978-1-0716-4985-5_7

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EMD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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