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Article

Characterizing heterogeneous cellular responses to perturbations.

Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 2008

Slack Michael D, Martinez Elisabeth D, Wu Lani F, Altschuler Steven J

Abstract excerpt

Cellular populations have been widely observed to respond heterogeneously to perturbation. However, interpreting the observed heterogeneity is an extremely challenging problem because of the complexity of possible cellular phenotypes, the large dimension of potential perturbations, and the lack of methods for separating meaningful biological information from noise. Here, we develop an image-based approach to...

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Identifiers

PMID: 19052231
DOI: 10.1073/pnas.0807038105
PMCID: PMC2614757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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