Article
Effects of DKK-3, a Wnt signaling inhibitor, on dendritic cell phenotype and T cell polarization.
Immunopharmacology and immunotoxicology - 1 Jan 2015
Mohammadpour Hemn, Pourfathollah Ali Akbar, Nikougoftar Zarif Mahin, Tahoori Mohammad Taher
Abstract excerpt
Wnt signaling plays crucial roles in regulation of a wide range of processes in different cell types including immune cells and, in particular, dendritic cells and T cells. Growing indications point out that Wnt pathway components modulate the both innate and adaptive immune responses through regulating DC functions. We investigated the effects of recombinant DKK-3 protein on the phenotype and biological...
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