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Article

Neddylation plays an important role in the regulation of murine and human dendritic cell function.

Blood - 19 Sept 2013

Mathewson Nathan, Toubai Tomomi, Kapeles Steven, Sun Yaping, Oravecz-Wilson Katherine, Tamaki Hiroya, Wang Ying, Hou Guoqing, Sun Yi, Reddy Pavan

Abstract excerpt

Posttranslational protein modifications (PTMs) are necessary for cells to function properly. The role of PTMs in regulating immune responses, specifically those mediated by dendritic cells (DCs), which are critical for both innate and adaptive immunity, is not well understood. Utilizing multiple but complementary approaches, we determined the role of an important but less understood type of PTM, namely,...

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Identifiers

PMID: 23863900
DOI: 10.1182/blood-2013-02-486373
PMCID: PMC3778550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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