Article
The canonical BMP signaling pathway is involved in human monocyte-derived dendritic cell maturation.
Immunology and cell biology - 1 Jul 2011
Martínez Víctor G, Hernández-López Carmen, Valencia Jaris, Hidalgo Laura, Entrena Ana, Zapata Agustín G, Vicente Angeles, Sacedón Rosa, Varas Alberto
Abstract excerpt
Bone morphogenetic proteins (BMPs), members of the transforming growth factor-β superfamily, are multifunctional polypeptides regulating a broad spectrum of functions in embryonic and adult tissues. Recent reports have demonstrated that BMPs regulate the survival, proliferation and differentiation of several cell types in the immune system. In this study, we investigate the effects of BMP signaling activation on...
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