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Article

Genomic aberrations in young and elderly breast cancer patients.

BMC medicine - 15 Oct 2015

Azim Hatem A, Nguyen Bastien, Brohée Sylvain, Zoppoli Gabriele, Sotiriou Christos

Abstract excerpt

BACKGROUND: Age at breast cancer diagnosis is a known prognostic factor. Previously, several groups including ours have shown that young age at diagnosis is associated with higher prevalence of basal-like tumors and aggressive tumor phenotypes. Yet the impact of age at diagnosis on the genomic landscape of breast cancer remains unclear. In this study, we examined the pattern of somatic mutations, chromosomal copy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26467651
DOI: 10.1186/s12916-015-0504-3
PMCID: PMC4606505

Genes

GATA3

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