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Article

An Integrative Analysis of the Age-Associated Genomic, Transcriptomic and Epigenetic Landscape across Cancers

2020-08-25

Abstract excerpt

Age is the most important risk factor for cancer, as cancer incidence and mortality increase with age. However, how molecular alterations in tumours differ among patients of different age remains largely unexplored. Here, using data from The Cancer Genome Atlas, we comprehensively characterised genomic, transcriptomic and epigenetic alterations in relation to patients’ age across cancer types. We showed that tumou...

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Literature Corpus work
f82cca9f-4ee6-56a7-aaf8-606cc6748830
DOI
10.1101/2020.08.25.266403
Open publication

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An Integrative Analysis of the Age-Associated Genomic, Transcriptomic and Epigenetic Landscape across CancersDOI 10.1101/2020.08.25.266403
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