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The Genomic Landscape of Breast Cancer in Young and Older Women.

Clinical breast cancer - 1 Oct 2024

Heeke Arielle L, Sha Wei, Feldman Rebecca, Fisher Julie, Hadzikadic-Gusic Lejla, Symanowski James T, White Richard L, Tan Antoinette R

Abstract excerpt

BACKGROUND: Young women with breast cancer (YWBC; ≤40 years) often have a poorer prognosis than older women with breast cancer (OWBC; ≥65 years). We explored molecular features of tumors from YWBC and OWBC to identify a biologic connection for these patterns. MATERIALS AND METHODS: We retrospectively analyzed the molecular profiles of 1879 breast tumors. Testing included immunohistochemistry (IHC), in situ...

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Identifiers

PMID: 39174364
DOI: 10.1016/j.clbc.2024.07.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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