Article
Integrated molecular profiling of young and elderly patients with triple-negative breast cancer indicates different biological bases and clinical management strategies.
Cancer - 15 Jul 2020
Ma Ding, Jiang Yi-Zhou, Xiao Yi, Xie Meng-Dan, Zhao Shen, Jin Xi, Xu Xiao-En, Shao Zhi-Ming
Abstract excerpt
BACKGROUND: Age at the time of breast cancer diagnosis not only predicts clinical outcome but also indicates distinct molecular characteristics that provide the rationale for appropriate treatment strategies. However, to the authors' knowledge, little is known regarding the molecular profile and biological basis of triple-negative breast cancers (TNBCs) occurring in young and elderly patients. METHODS: Using the...
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