Article
Molecular analyses of triple-negative breast cancer in the young and elderly.
Breast cancer research : BCR - 10 Feb 2021
Aine Mattias, Boyaci Ceren, Hartman Johan, Häkkinen Jari, Mitra Shamik, Campos Ana Bosch, Nimeus Emma, Ehinger Anna, Vallon-Christersson Johan, Borg Åke, Staaf Johan
Abstract excerpt
BACKGROUND: Breast cancer in young adults has been implicated with a worse outcome. Analyses of genomic traits associated with age have been heterogenous, likely because of an incomplete accounting for underlying molecular subtypes. We aimed to resolve whether triple-negative breast cancer (TNBC) in younger versus older patients represent similar or different molecular diseases in the context of genetic and...
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