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Article

A common TLR1 polymorphism is associated with higher parasitaemia in a Southeast Asian population with Plasmodium falciparum malaria.

Malaria journal - 6 Jan 2016

Hahn William O, Harju-Baker Susanna, Erdman Laura K, Krudsood Srivicha, Kain Kevin C, Wurfel Mark M, Liles Wayne C

Abstract excerpt

BACKGROUND: The factors leading to poor outcomes in malaria infection are incompletely understood. Common genetic variation exists in the human genes for Toll like receptors (TLRs) that alter host responses to pathogen-associated molecular patterns. Genetic variation in TLR1 and TLR6 could alter the risk of development of complicated malaria and ability of the host to control the parasite burden during acute...

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Source

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Identifiers

PMID: 26738805
DOI: 10.1186/s12936-015-1071-y
PMCID: PMC4704253

Genes

TLR1
TLR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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