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Article

A meta-analysis of TLR4 and TLR9 SNPs implicated in severe malaria.

Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2000

Dhangadamajhi Gunanidhi, Kar Avishek, Rout Ronnaly, Dhangadamajhi Prabin

Abstract excerpt

Toll-like receptors (TLRs) are critical mediators of the inflammatory response to malarial infection, and gene polymorphisms affecting TLR function may be partially responsible for inter-individual variation in disease manifestation. However, there are inconsistencies in the associations of common genetic variants of TLR4 (D299G) and TLR9 (T-1237C and T-1486C) with malaria outcome. A comprehensive search was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28562749
DOI: 10.1590/0037-8682-0475-2016

Genes

TLR4
TLR9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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