Article
Influence of MCHR2 and MCHR2-AS1 Genetic Polymorphisms on Body Mass Index in Psychiatric Patients and In Population-Based Subjects with Present or Past Atypical Depression.
PloS one - 1 Jan 2015
Delacrétaz Aurélie, Preisig Martin, Vandenberghe Frederik, Saigi Morgui Nuria, Quteineh Lina, Choong Eva, Gholam-Rezaee Mehdi, Kutalik Zoltan, Magistretti Pierre, Aubry Jean-Michel, von Gunten Armin, Castelao Enrique, Vollenweider Peter, Waeber Gerard, Conus Philippe, Eap Chin B
Abstract excerpt
Obesity development during psychotropic treatments represents a major health issue in psychiatry. Melanin-concentrating hormone receptor 2 (MCHR2) is a central receptor involved in energy homeostasis. MCHR2 shares its promoter region with MCHR2-AS1, a long antisense non-coding RNA. The aim of this study was to determine whether tagging single nucleotide polymorphisms (tSNPs) of MCHR2 and MCHR2-AS1 are associated...
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