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Article

Obesity and atypical depression symptoms: findings from Mendelian randomization in two European cohorts.

Translational psychiatry - 4 Feb 2021

Pistis Giorgio, Milaneschi Yuri, Vandeleur Caroline L, Lasserre Aurélie M, Penninx Brenda W J H, Lamers Femke, Boomsma Dorret I, Hottenga Jouke-Jan, Marques-Vidal Pedro, Vollenweider Peter, Waeber Gérard, Aubry Jean-Michel, Preisig Martin, Kutalik Zoltán

Abstract excerpt

Studies considering the causal role of body mass index (BMI) for the predisposition of major depressive disorder (MDD) based on a Mendelian Randomization (MR) approach have shown contradictory results. These inconsistent findings may be attributable to the heterogeneity of MDD; in fact, several studies have documented associations between BMI and mainly the atypical subtype of MDD. Using a MR approach, we...

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Identifiers

PMID: 33542229
DOI: 10.1038/s41398-021-01236-7
PMCID: PMC7862438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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